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Article

Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation.

Human molecular genetics - 1 Jul 2008

White Julia H, Chiano Mathias, Wigglesworth Mark, Geske Robert, Riley John, White Nicola, Hall Simon, Zhu Guohua, Maurio Frank, Savage Tony, Anderson Wayne, Cordy Joanna, Ducceschi Melissa, Vestbo Jorgen, Pillai Sreekumar G

Abstract excerpt

Asthma is a multifactorial disease, in which the intricate interplay between genetic and environmental factors underlies the overall phenotype of the disease. Using a genome-wide scan for linkage in a population comprising of Danish families, we identified a novel linked locus on chromosome 1qter (LOD 3.6, asthma) and supporting evidence for this locus was identified for both asthma and atopic-asthma phenotypes...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18344558
DOI: 10.1093/hmg/ddn087

Genes

OPN3
CHML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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