Article
Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci.
The Journal of allergy and clinical immunology - 1 Aug 2006
Kurz Thorsten, Hoffjan Sabine, Hayes M Geoffrey, Schneider Dan, Nicolae Raluca, Heinzmann Andrea, Jerkic Sylvija P, Parry Rod, Cox Nancy J, Deichmann Klaus A, Ober Carole
Abstract excerpt
BACKGROUND: Genome-wide linkage scans to identify asthma susceptibility loci have revealed many linked regions, including a broad region on chromosome 5p. OBJECTIVE: To identify a 5p-linked asthma or bronchial hyperresponsiveness (BHR) locus. METHODS: We performed fine mapping and positional candidate studies of this region in the Hutterites and an outbred case-control sample from Germany by genotyping 89 single...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
