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Article

Gene expression deregulation by KRAS G12D and G12V in a BRAF V600E context.

Molecular cancer - 16 Dec 2008

Monticone Massimiliano, Biollo Emanuela, Maffei Massimo, Donadini Alessandra, Romeo Francesco, Storlazzi Clelia Tiziana, Giaretti Walter, Castagnola Patrizio

Abstract excerpt

BACKGROUND: KRAS and BRAF mutations appear of relevance in the genesis and progression of several solid tumor types but the co-occurrence and interaction of these mutations have not yet been fully elucidated. Using a microsatellite stable (MSS) colorectal cancer (CRC) cell line (Colo741) having m...

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Source

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Identifiers

PMID: 19087308
DOI: 10.1186/1476-4598-7-92
PMCID: PMC2615043

Genes

KRAS
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19087308-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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