Article

KRAS mutation-selective requirement for ACSS2 in colorectal adenoma formation.

2024-02-22

Abstract excerpt

<title>Abstract</title> <p>Oncogenic <italic>KRAS </italic>mutations are prevalent in colorectal cancer (CRC) and are associated with poor prognosis and resistance to therapy. There is a substantial diversity of <italic>KRAS </italic>mutant alleles observed in CRC. Emerging clinical and experimental analysis of common <italic>KRAS</italic> mutations suggest that each mutation differently influences the clinical p...

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Literature Corpus work: 0937ee14-335f-549c-9707-47401d749d25
DOI: 10.21203/rs.3.rs-3931415/v1

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