Article
No association of single nucleotide polymorphisms in one-carbon metabolism genes with prostate cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2008
Stevens Victoria L, Rodriguez Carmen, Sun Juzhong, Talbot Jeffrey T, Thun Michael J, Calle Eugenia E
Abstract excerpt
One-carbon metabolism mediates the interconversion of folates for the synthesis of precursors used in DNA synthesis, repair, and methylation. Inadequate folate nutrition or compromised metabolism can disrupt these processes and facilitate carcinogenesis. In this study, we investigated associations of 39 candidate single nucleotide polymorphisms (SNP) in 9 one-carbon metabolism genes with risk of prostate cancer...
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