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Article

Perils in the use of linkage disequilibrium for fine gene mapping: simple insights from population genetics.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2008

Gorroochurn Prakash

Abstract excerpt

It is generally believed that genome-wide association (GWA) studies stand a good chance for finding susceptibility genes for common complex diseases. Although the results thus far have been somewhat promising, there are still many inherent difficulties and many initial associations do not get replicated. The common strategy in GWA studies has been that of selecting the most statistically significant single...

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PMID: 19064541
DOI: 10.1158/1055-9965.EPI-08-0717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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