Article
Fine-scale mapping using Hardy-Weinberg disequilibrium.
Annals of human genetics - 1 Mar 2001
Jiang R, Dong J, Wang D, Sun F Z
Abstract excerpt
Hardy-Weinberg disequilibrium (HWD) among affected individuals has recently been proposed for fine-scale mapping of disease susceptibility genes. We investigate the statistical properties of several available HWD measures and develop a new HWD measure J for fine-scale mapping. It is shown both theoretically and through simulations that the available HWD measures depend not only on the genetic distance between the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
