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Article

The stringent response blocks DNA replication outside the ori region in Bacillus subtilis and at the origin in Escherichia coli.

Journal of molecular biology - 20 Jun 1991

Levine A, Vannier F, Dehbi M, Henckes G, Séror S J

Abstract excerpt

When the Bacillus subtilis dnaB37 mutant, defective in initiation, is returned to permissive temperature after growth at 45 degrees C, DNA replication is synchronized. Under these conditions, we have shown previously that DNA replication is inhibited when the Stringent Response is induced by the amino acid analogue, arginine hydroxamate. We have now shown, using DNA-DNA hybridization analysis, that substantial...

Topics

Arginine
Bacillus subtilis
Bacterial Proteins
Chromosomes, Bacterial
DNA Replication
DNA, Bacterial
Escherichia coli
Gene Expression Regulation, Bacterial
Kinetics
Mutation
Nucleic Acid Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Temperature

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Identifiers

PMID: 1905358
DOI: 10.1016/0022-2836(91)90657-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1905358-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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