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Article

Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells.

American journal of physiology. Cell physiology - 1 Feb 2009

Klein Hélène, Garneau Line, Trinh Nguyen Thu Ngan, Privé Anik, Dionne François, Goupil Eugénie, Thuringer Dominique, Parent Lucie, Brochiero Emmanuelle, Sauvé Rémy

Abstract excerpt

The vectorial transport of ions and water across epithelial cells depends to a large extent on the coordination of the apical and basolateral ion fluxes with energy supply. In this work we provide the first evidence for a regulation by the 5'-AMP-activated protein kinase (AMPK) of the calcium-activated potassium channel KCa3.1 expressed at the basolateral membrane of a large variety of epithelial cells....

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Identifiers

PMID: 19052260
DOI: 10.1152/ajpcell.00418.2008
PMCID: PMC2643852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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