Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Down-regulation of the Na+-coupled phosphate transporter NaPi-IIa by AMP-activated protein kinase.

Kidney & blood pressure research - 1 Jan 2013

Dërmaku-Sopjani Miribane, Almilaji Ahmad, Pakladok Tatsiana, Munoz Carlos, Hosseinzadeh Zohreh, Blecua María, Sopjani Mentor, Lang Florian

Abstract excerpt

BACKGROUND/AIMS: The Na(+)-coupled phosphate transporter NaPi-IIa is the main carrier accomplishing renal tubular phosphate reabsorption. It is driven by the electrochemical Na(+) gradient across the apical cell membrane, which is maintained by Na(+) extrusion across the basolateral cell membrane through the Na(+)/K(+) ATPase. The operation of NaPi-IIa thus requires energy in order to avoid cellular Na(+)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AMP-Activated Protein Kinases
Share to Catalytic Domain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Down-Regulation

Share to Luminescence

Share to Mutation

Share to Oocytes

Share to Protein Kinase Inhibitors

Share to Xenopus laevis

Source

Identifiers

PMID: 24356547
DOI: 10.1159/000355735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Down-regulation of the Na+-coupled phosphate transporter NaPi-IIa by AMP-activated protein kinase.PMID 24356547Read ↗

Downregulation of the renal outer medullary K(+) channel ROMK by the AMP-activated protein kinase.Semantic proximity Read ↗

Inhibition of Kir2.1 (KCNJ2) by the AMP-activated protein kinase.Semantic proximity Read ↗

AMPK controls epithelial Na(+) channels through Nedd4-2 and causes an epithelial phenotype when mutated.Semantic proximity Read ↗

Sodium-dependent phosphate cotransporters: lessons from gene knockout and mutation studies.Semantic proximity Read ↗

Downregulation of Kv1.5 K channels by the AMP-activated protein kinase.Semantic proximity Read ↗

Chronic activation of AMP-activated protein kinase leads to early-onset polycystic kidney phenotype.Semantic proximity Read ↗

Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells.Semantic proximity Read ↗

Down-regulation of Na+-coupled glutamate transporter EAAT3 and EAAT4 by AMP-activated protein kinase.Semantic proximity Read ↗

Stimulation of the intestinal phosphate transporter SLC34A2 by the protein kinase mTOR.Semantic proximity Read ↗

AMPK phosphorylation of the β1Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells.Semantic proximity Read ↗

[Pump activity-independent novel functions of Na+/K+ ATPase in the nervous systems].Semantic proximity Read ↗

Multiple pathways for protein phosphatase 1 (PP1) regulation of Na-K-2Cl cotransporter (NKCC1) function: the N-terminal tail of the Na-K-2Cl cotransporter serves as a regulatory scaffold for Ste20-related proline/alanine-rich kinase (SPAK) AND PP1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.