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Article

Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cells.

American journal of physiology. Cell physiology - 1 May 2003

Hallows Kenneth R, Kobinger Gary P, Wilson James M, Witters Lee A, Foskett J Kevin

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-activated, ATP-gated Cl(-) channel and cellular conductance regulator, but the detailed mechanisms of CFTR regulation and its regulation of other transport proteins remain obscure. We previously identified the metabolic sensor AMP-activated protein kinase (AMPK) as a novel protein interacting with CFTR and found that AMPK phosphorylated CFTR...

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Source

Identifiers

PMID: 12519745
DOI: 10.1152/ajpcell.00227.2002

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cells.PMID 12519745Read ↗

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