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Article

Programs for calculating the statistical powers of detecting susceptibility genes in case-control studies based on multistage designs.

Bioinformatics (Oxford, England) - 15 Jan 2009

Kitamura Nobutaka, Akazawa Kouhei, Miyashita Akinori, Kuwano Ryozo, Toyabe Shin-ichi, Nakamura Junichiro, Nakamura Norihito, Sato Tatsuhiko, Hoque M Aminul

Abstract excerpt

MOTIVATION: A two-stage association study is the most commonly used method among multistage designs to efficiently identify disease susceptibility genes. Recently, some SNP studies have utilized more than two stages to detect disease genes. However, there are few available programs for calculating statistical powers and positive predictive values (PPVs) of arbitrary n-stage designs. RESULTS: We developed programs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19043077
DOI: 10.1093/bioinformatics/btn616
PMCID: PMC2639008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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