Comparisons of power of statistical methods for gene-environment interaction analyses.

Abstract excerpt

Any genome-wide analysis is hampered by reduced statistical power due to multiple comparisons. This is particularly true for interaction analyses, which have lower statistical power than analyses of associations. To assess gene-environment interactions in population settings we have recently proposed a statistical method based on a modified two-step approach, where first genetic loci are selected by their...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Computer Simulation
• Share to Data Interpretation, Statistical
• Share to False Positive Reactions