Article
Prioritize and select SNPs for association studies with multi-stage designs.
Journal of computational biology : a journal of computational molecular cell biology - 1 Apr 2008
Li Jing
Abstract excerpt
Large-scale whole genome association studies are increasingly common, due in large part to recent advances in genotyping technology. With this change in paradigm for genetic studies of complex diseases, it is vital to develop valid, powerful, and efficient statistical tools and approaches to evaluate such data. Despite a dramatic drop in genotyping costs, it is still expensive to genotype thousands of individuals...
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