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Article

Evaluating rare variants under two-stage design.

Journal of human genetics - 1 Jun 2012

Li Qizhai, Pan Dongdong, Yue Weihua, Gao Ying, Yu Kai

Abstract excerpt

Current genome-wide association studies (GWAS) focusing on relatively common single-nucleotide polymorphisms (SNPs) usually adopt a cost-effective multi-staged design in which a proportion of the total samples are genotyped using a commercial SNP array with a reasonably good coverage of the whole genome at the initial stage, and a list of promising SNPs are further genotyped and evaluated on the remaining samples...

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PMID: 22572736
DOI: 10.1038/jhg.2012.33

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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