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Article

Influence of VKORC1 gene polymorphisms on the effect of oral vitamin K supplementation in over-anticoagulated patients.

Journal of thrombosis and thrombolysis - 1 Apr 2014

Zuchinali Priccila, Souza Gabriela C, Aliti Graziella, Botton Mariana R, Goldraich Lívia, Santos Katia G, Hutz Mara H, Bandinelli Eliane, Rohde Luis E

Abstract excerpt

Significant inter-individual variability on the effect of vitamin K to reverse overanticoagulation has been identified. Genetic polymorphisms of the vitamin K epoxide reductase complex subunit 1 (VKORC1) gene might explain in part this variability. The objective of this study was to evaluate the influence of VKORC1 -1639G>A and 3730G>A polymorphisms on the effect of oral vitamin K supplementation in...

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Source

Identifiers

PMID: 23771743
DOI: 10.1007/s11239-013-0947-3

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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