Article
Characterization of a functional polymorphism in the 3' UTR of SLC6A4 and its association with drinking intensity.
Alcoholism, clinical and experimental research - 1 Feb 2009
Seneviratne Chamindi, Huang Weihua, Ait-Daoud Nassima, Li Ming D, Johnson Bankole A
Abstract excerpt
BACKGROUND: The propensity for severe drinking is hypothesized to be regulated by differential expression of serotonin transporter gene (SLC6A4) in the human brain. The SLC6A4 promoter region 5-HTTLPR has been examined previously as a candidate polymorphic variant associated with severe drinking. In this study, we investigated whether other SLC6A4 single nucleotide polymorphisms (SNPs) are associated with...
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