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Article

5-HTTLPR genotype and daily negative mood moderate the effects of sertraline on drinking intensity.

Addiction biology - 1 Nov 2013

Kranzler Henry R, Armeli Stephen, Tennen Howard, Covault Jonathan

Abstract excerpt

We previously reported moderating effects of age of onset of alcohol dependence (AD) and a functional polymorphism (5-HTTLPR) in the gene encoding the serotonin transporter protein in a sample of 134 individuals participating in a 12-week, placebo-controlled trial of sertraline. To understand more fully the effects seen in that study, we examined moderation by negative moods reported each evening, with nighttime...

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Identifiers

PMID: 23145795
DOI: 10.1111/adb.12007
PMCID: PMC3578002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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