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Article

Polymorphism in the serotonin transporter gene and response to treatment in African American cocaine and alcohol-abusing individuals.

Addiction biology - 1 Sept 2005

Mannelli Paolo, Patkar Ashwin A, Murray Heather W, Certa Kenneth, Peindl Kathleen, Mattila-Evenden Marja, Berrettini Wade H

Abstract excerpt

The serotonin transporter (5-HTT) regulates serotonin transmission and modulates behavioral effects of drug of abuse. A polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) yielding a short (S) and long (L) allele has been associated with severity of substance abuse. The aims of the study were to investigate whether 5-HTTLPR genotypes differed in their response to treatment in cocaine-...

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Source

Identifiers

PMID: 16109588
DOI: 10.1080/13556210500235540

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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