Article
Drinking histories in alcohol-use-disordered youth: preliminary findings on relationships to platelet serotonin transporter expression with genotypes of the serotonin transporter.
Journal of studies on alcohol and drugs - 1 Nov 2009
Dawes Michael A, Roache John D, Javors Martin A, Bergeson Susan E, Richard Dawn M, Mathias Charles W, Ait-Daoud Nassima, Dougherty Donald M, Johnson Bankole A
Abstract excerpt
OBJECTIVE: The serotonin (5-HT) transporter (5-HTT) is thought to play a key role in the onset of alcohol use, with potential behavioral and biological mechanisms mediated by the level of 5-HT in the synapse and in cerebral spinal fluid. Although 5-HT dysregulation has been related to poor impulse control, the biological mechanism is unknown, although functional control of the serotonergic system has been shown...
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