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Article

Association study of alcoholism subtypes with a functional promoter polymorphism in the serotonin transporter protein gene.

Alcoholism, clinical and experimental research - 1 Sept 2002

Kranzler Henry, Lappalainen Jaakko, Nellissery Maggie, Gelernter Joel

Abstract excerpt

BACKGROUND: Association studies of a reportedly functional polymorphism in the promoter region (5'-HTTLPR) of the gene encoding the serotonin transporter protein (genetic locus SLC6A4) in alcoholics have yielded conflicting results. The most frequently observed alleles of the 5'-HTTLPR polymorphism are the short and long variants; the short variant is associated with lower transcriptional activity of the SLC6A4...

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Identifiers

PMID: 12351926
DOI: 10.1097/01.ALC.0000030840.48315.40

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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