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Article

High-throughput detection of glutathione s-transferase polymorphic alleles in a pediatric cancer population.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2004

Barnette Phillip, Scholl Rebecca, Blandford Mary, Ballard Linda, Tsodikov Alexander, Magee Jalene, Williams Susana, Robertson Margaret, Ali-Osman Francis, Lemons Richard, Keller Charles

Abstract excerpt

Polymorphisms of glutathione S-transferase (GST) enzymes have been correlated with altered risk of several cancers, as well as altered response and toxicity from cancer chemotherapy. We report a low cost, highly reproducible and specific PCR-based high-throughput assay for genotyping different GSTs designed for use in large clinical trials. In comparison to an alternative genotyping method (single nucleotide...

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Source

Identifiers

PMID: 14973099
DOI: 10.1158/1055-9965.epi-03-0178

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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