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Article

Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of Hec1.

Current biology : CB - 25 Nov 2008

Guimaraes Geoffrey J, Dong Yimin, McEwen Bruce F, Deluca Jennifer G

Abstract excerpt

Accurate chromosome segregation is dependent upon stable attachment of kinetochores to spindle microtubules during mitosis. A long-standing question is how kinetochores maintain stable attachment to the plus ends of dynamic microtubules that are continually growing and shortening. The Ndc80 complex is essential for persistent end-on kinetochore-microtubule attachment in cells [1, 2], but how the Ndc80 complex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19026543
DOI: 10.1016/j.cub.2008.08.012
PMCID: PMC2753282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of Hec1.PMID 19026543Read ↗

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