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Article

A redundant function for the N-terminal tail of Ndc80 in kinetochore-microtubule interaction in Saccharomyces cerevisiae.

Genetics - 1 Oct 2012

Demirel Pinar B, Keyes Brice E, Chaterjee Mandovi, Remington Courtney E, Burke Daniel J

Abstract excerpt

The N-terminal tail of Ndc80 is essential for kinetochore-microtubule binding in human cells but is not required for viability in yeast. We show that the yeast Ndc80 tail is required for timely mitotic progression and accurate chromosome segregation. The tail is essential when cells are limited f...

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Identifiers

PMID: 22851650
DOI: 10.1534/genetics.112.143818
PMCID: PMC3454895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22851650-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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