Article
c-Ki-ras point mutations in ductectatic-type mucinous cystic neoplasms of the pancreas.
Japanese journal of cancer research : Gann - 1 Oct 1991
Yanagisawa A, Kato Y, Ohtake K, Kitagawa T, Ohashi K, Hori M, Takagi K, Sugano H
Abstract excerpt
Ductectatic-type mucinous cystic neoplasms of the pancreas constitute a recently recognized new human pancreatic tumor entity. Examination for the presence of point mutations at codon 12 of K-ras by oligonucleotide hybridization in 5 adenomas and 3 carcinomas revealed alteration in 3 and 2, respectively. In 4 of these positive cases, the transition was GGT----GAT (Gly----Asp) with the remaining one, found in a...
Topics
- Adenoma
- Base Sequence
- Cystadenoma
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Oligonucleotides
- Pancreatic Neoplasms
- Polymerase Chain Reaction
