Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microsatellite instability and K-ras mutations in gastric adenomas, with reference to associated gastric cancers.

Cancer detection and prevention - 1 Jan 1999

Isogaki J, Shinmura K, Yin W, Arai T, Koda K, Kimura T, Kino I, Sugimura H

Abstract excerpt

Gastric adenomas are often detected in the stomach resected for gastric cancer. Previous investigation have revealed that the prevalence of their malignant transformation is generally low, but the frequent coexistence with carcinoma suggests that they may share some common processes with gastric cancer in tumorigenesis. In contrast to the cumulative information about genetic alterations in gastric cancer,...

Topics

Adenoma
Aged
Aged, 80 and over
DNA, Neoplasm
DNA-Binding Proteins
Genes, ras
Genetic Markers
Humans
Microsatellite Repeats
Middle Aged
Multidrug Resistance-Associated Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

MutS Homolog 3 Protein

Mutation

Receptors, Transforming Growth Factor beta

Stomach Neoplasms

Source

Identifiers

PMID: 10336999
DOI: 10.1046/j.1525-1500.1999.99020.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microsatellite instability and K-ras mutations in gastric adenomas, with reference to associated gastric cancers.PMID 10336999Read ↗

Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma.Semantic proximity Read ↗

Genetic alterations in gastric adenomas of intestinal and foveolar phenotypes.Semantic proximity Read ↗

Microsatellite instability in hyperplastic and adenomatous polyps of the stomach.Semantic proximity Read ↗

Microsatellite instability in synchronous gastric carcinomas.Semantic proximity Read ↗

Microsatellite alterations and target gene mutations in the early stages of multiple gastric cancer.Semantic proximity Read ↗

Microsatellite alterations in adenoma and differentiated adenocarcinoma of the stomach.Semantic proximity Read ↗

Synchronous multiple primary gastrointestinal cancer exhibits frequent microsatellite instabilitySemantic proximity Read ↗

Higher frequency of point mutations in the c-K-ras 2 gene in human colorectal adenomas with severe atypia than in carcinomas.Semantic proximity Read ↗

Lower incidence of K-ras codon 12 mutation in flat colorectal adenomas than in polypoid adenomas.Semantic proximity Read ↗

Mutations in the RAS/RAF/MAP kinase pathway commonly occur in gallbladder adenomas but are uncommon in gallbladder adenocarcinomas.Semantic proximity Read ↗

Point mutation of c-Ki-ras oncogene in gastric adenoma and adenocarcinoma with tubular differentiation.Semantic proximity Read ↗

Variation in K-ras codon 12 point mutation rate with histological atypia within individual colorectal tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.