p53 gene mutations in gastric adenomas.

doi:10.1007/BF02899260

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Article

p53 gene mutations in gastric adenomas.

Virchows Archiv. B, Cell pathology including molecular pathology - 1 Jan 1993

Tohdo H, Yokozaki H, Haruma K, Kajiyama G, Tahara E

Abstract excerpt

p53 gene alterations in ten gastric adenomas and one carcinoma arising in an adenoma were analyzed by deoxynucleotide sequencing. Three (30%) of the ten gastric adenomas had p53 gene mutations, one adenoma showing a frameshift mutation and two others showing silent mutations. In addition, two mis...

Topics

Adenoma
Base Sequence
Codon
Frameshift Mutation
Genes, p53
Humans
Immunohistochemistry
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Stomach Neoplasms

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