Article
Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer.
Carcinogenesis - 1 Jan 2009
Freedman Neal D, Ahn Jiyoung, Hou Lifang, Lissowska Jolanta, Zatonski Witold, Yeager Meredith, Chanock Stephen J, Chow Wong Ho, Abnet Christian C
Abstract excerpt
Androgens and estrogens may play a role in gastric cancer etiology. To investigate the association of gastric cancer with single-nucleotide polymorphisms (SNPs) in six genes (COMT, CYP1B1, CYP17A1, CYP19A1, HSD17B1 and SHBG) involved in estrogen and androgen synthesis and metabolism, 58 haplotype...
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