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Polymorphisms in the CYP19A1 (aromatase) gene and endometrial cancer risk in Chinese women.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2007

Tao Meng Hua, Cai Qiuyin, Zhang Zuo-Feng, Xu Wang-Hong, Kataoka Nobuhiko, Wen Wanqing, Xiang Yong-Bing, Zheng Wei, Shu Xiao Ou

Abstract excerpt

Aromatase, encoded by the CYP19A1 gene, is a key enzyme in estradiol biosynthesis, which catalyzes the conversion of androstenedione and testosterone to estrone and estradiol, respectively. Given the critical role of estrogen in the development of endometrial cancer risk, we evaluated genetic polymorphisms of the CYP19A1 gene, including rs1065779, rs700519, rs28566535, rs752760, and rs1870050, in association with...

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PMID: 17507620
DOI: 10.1158/1055-9965.EPI-06-1012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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