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High Polygenic Risk Scores Positively Associated with Gastric Cancer Risk Interact with Coffee and Polyphenol Intake and Smoking Status in Korean Adults.

Nutrients - 27 Sept 2024

Liu Meiling, Song Sang-Shin, Park Sunmin

Abstract excerpt

BACKGROUND/OBJECTIVES: This study investigated the relationship between single nucleotide polymorphisms (SNPs) and gastric cancer (GC) risk, while also examining the interaction of genetic factors with lifestyle variables including the nutrient and bioactive compound intake in Korean adults of a large hospital-based cohort. METHODS: We conducted a genome-wide association study (GWAS) comparing GC patients (n =...

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PMID: 39408230
DOI: 10.3390/nu16193263
PMCID: PMC11478441

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