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Linking CDH1 SNPs to gastric cancer risk: a comprehensive analysis of rs16260, rs13689, and rs9929218.

Molecular biology reports - 17 Nov 2024

Aslan Fırat, Almalı Necat, Kaya Zehra, Güven Mustafa, Şahin Elif Sena, Özdemir Abdulselam, Duran Seren, Binici Serhat, Karan Burak Muğdat, Uygur Serhat

Abstract excerpt

OBJECTIVE: Single nucleotide polymorphisms (SNPs) are linked to carcinogenesis. Pathogenic variants in the CDH1 gene are associated with gastric cancer. This study examines the genotype and allele frequencies of three SNPs (rs16260, rs13689, and rs9929218) in the CDH1 gene and their relationship with gastric cancer risk. MATERIALS AND METHODS: The study involved 105 gastric cancer patients with pathology results...

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PMID: 39550749
DOI: 10.1007/s11033-024-10094-7

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