Article
Genetic susceptibility factors on genes involved in the steroid hormone biosynthesis pathway and progesterone receptor for gastric cancer risk.
PloS one - 1 Jan 2012
Cho Lisa Y, Yang Jae Jeong, Ko Kwang-Pil, Ma Seung Hyun, Shin Aesun, Choi Bo Youl, Han Dong Soo, Song Kyu Sang, Kim Yong Sung, Chang Soung-Hoon, Shin Hai-Rim, Kang Daehee, Yoo Keun-Young, Park Sue K
Abstract excerpt
BACKGROUND: The objective of the study was to investigate the role of genes (HSD3B1, CYP17A1, CYP19A1, HSD17B2, HSD17B1) involved in the steroid hormone biosynthesis pathway and progesterone receptor (PGR) in the etiology of gastric cancer in a population-based two-phase genetic association study. METHODS: In the discovery phase, 108 candidate SNPs in the steroid hormone biosynthesis pathway related genes and PGR...
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