Article
Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China.
Carcinogenesis - 1 Apr 2009
Park Sue K, Andreotti Gabriella, Sakoda Lori C, Gao Yu-Tang, Rashid Asif, Chen Jinbo, Chen Bingshu E, Rosenberg Philip S, Shen Ming-Chang, Wang Bing-Sheng, Han Tian-Quan, Zhang Bai-He, Yeager Meredith, Chanock Stephen, Hsing Ann W
Abstract excerpt
Biliary tract cancers, encompassing gallbladder, extrahepatic bile duct and ampulla of Vater cancers, are uncommon but often fatal malignancies. Hormone-related factors, including parity, oral contraceptive use, obesity, and gallstones, have been implicated in the etiology of these cancers. To further clarify the role of hormones in biliary tract cancers and biliary stones, we genotyped 18 single-nucleotide...
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