Article
Genetic variants in sex hormone metabolic pathway genes and risk of esophageal squamous cell carcinoma.
Carcinogenesis - 1 May 2013
Hyland Paula L, Freedman Neal D, Hu Nan, Tang Ze-Zhong, Wang Lemin, Wang Chaoyu, Ding Ti, Fan Jin-Hu, Qiao You-Lin, Golozar Asieh, Wheeler William, Yu Kai, Yuenger Jeff, Burdett Laurie, Chanock Stephen J, Dawsey Sanford M, Tucker Margaret A, Goldstein Alisa M, Abnet Christian C, Taylor Philip R
Abstract excerpt
In China, esophageal cancer is the fourth leading cause of cancer death where essentially all cases are histologically esophageal squamous cell carcinoma (ESCC), in contrast to esophageal adenocarcinoma in the West. Globally, ESCC is 2.4 times more common among men than women and recently it has been suggested that sex hormones may be associated with the risk of ESCC. We examined the association between genetic...
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