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Article

Smoking and Parkinson's disease: does nicotine affect alpha-synuclein fibrillation?

Biochimica et biophysica acta - 1 Feb 2009

Hong Dong-Pyo, Fink Anthony L, Uversky Vladimir N

Abstract excerpt

alpha-synuclein is a small presynaptic protein (14,460 D) that is abundantly distributed in the brain. Although, its function is unknown, the aggregated form of alpha-synuclein is a pathological hallmark of several neurodegenerative diseases, including Parkinson's disease (PD). Epidemiological st...

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Identifiers

PMID: 19013262
DOI: 10.1016/j.bbapap.2008.09.026
PMCID: PMC2647853

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AFM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19013262-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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