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Protective effects of saffron and its constituent crocetin to motor symptoms, short life span and rough-eyed phenotypes in the fly models of Parkinson’s disease <i>in vivo</i>

2020-12-07

Abstract excerpt

Parkinson’s disease (PD) is a common neurodegenerative disorder with motor symptoms linked to the loss of dopaminergic neurons in the brain. α-Synuclein is an aggregation-prone neural protein that plays a role in the pathogenesis of PD. In our previous paper, we found that saffron; the stigma of Crocus sativus Linné ( Iridaceae ), and its constituents (crocin and crocetin) suppressed aggregation of α-synuclein a...

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Literature Corpus work
31893772-3557-5e8e-8b42-f82083d7b5f6
DOI
10.1101/2020.12.06.408997
Open publication

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Protective effects of saffron and its constituent crocetin to motor symptoms, short life span and rough-eyed phenotypes in the fly models of Parkinson’s disease <i>in vivo</i>DOI 10.1101/2020.12.06.408997
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