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Article

Align human interactome with phenome to identify causative genes and networks underlying disease families.

Bioinformatics (Oxford, England) - 1 Jan 2009

Wu Xuebing, Liu Qifang, Jiang Rui

Abstract excerpt

MOTIVATION: Understanding the complexity in gene-phenotype relationship is vital for revealing the genetic basis of common diseases. Recent studies on the basis of human interactome and phenome not only uncovers prevalent phenotypic overlap and genetic overlap between diseases, but also reveals a modular organization of the genetic landscape of human diseases, providing new opportunities to reduce the complexity...

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PMID: 19010805
DOI: 10.1093/bioinformatics/btn593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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