Article
The expanded human disease network combining protein-protein interaction information.
European journal of human genetics : EJHG - 1 Jul 2011
Zhang Xuehong, Zhang Ruijie, Jiang Yongshuai, Sun Peng, Tang Guoping, Wang Xing, Lv Hongchao, Li Xia
Abstract excerpt
The human disease network (HDN) has become a powerful tool for revealing disease-disease associations. Some studies have shown that genes that share similar or same disease phenotypes tend to encode proteins that interact with each other. Therefore, protein-protein interactions (PPIs) may help us to further understand the relationships between diseases with overlapping clinical phenotypes. In this study, we...
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