Article
Network-based global inference of human disease genes.
Molecular systems biology - 1 Jan 2008
Wu Xuebing, Jiang Rui, Zhang Michael Q, Li Shao
Abstract excerpt
Deciphering the genetic basis of human diseases is an important goal of biomedical research. On the basis of the assumption that phenotypically similar diseases are caused by functionally related genes, we propose a computational framework that integrates human protein-protein interactions, disease phenotype similarities, and known gene-phenotype associations to capture the complex relationships between...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.