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Constructing an integrated gene similarity network for the identification of disease genes

1 Sept 2017

Abstract excerpt

BACKGROUND: Discovering novel genes that are involved human diseases is a challenging task in biomedical research. In recent years, several computational approaches have been proposed to prioritize candidate disease genes. Most of these methods are mainly based on protein-protein interaction (PPI) networks. However, since these PPI networks contain false positives and only cover less half of known human genes,...

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PMID: 29297379
DOI: 10.1186/s13326-017-0141-1

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