Article
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development.
PLoS genetics - 1 Nov 2008
Etheridge S Leah, Ray Saugata, Li Shuangding, Hamblet Natasha S, Lijam Nardos, Tsang Michael, Greer Joy, Kardos Natalie, Wang Jianbo, Sussman Daniel J, Chen Ping, Wynshaw-Boris Anthony
Abstract excerpt
Dishevelled (Dvl) proteins are important signaling components of both the canonical beta-catenin/Wnt pathway, which controls cell proliferation and patterning, and the planar cell polarity (PCP) pathway, which coordinates cell polarity within a sheet of cells and also directs convergent extension cell (CE) movements that produce narrowing and elongation of the tissue. Three mammalian Dvl genes have been...
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