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Article

Dishevelled: in vivo roles of a multifunctional gene family during development.

Current topics in developmental biology - 1 Jan 2012

Wynshaw-Boris Anthony

Abstract excerpt

Dishevelled proteins are highly conserved throughout evolution and participate in canonical and noncanonical Wnt pathways. In particular, Dvls participate in the planar cell polarity (PCP) pathway that is important for a variety of developmental processes. There are three Dvl genes in mammals. These three genes are highly conserved and broadly expressed throughout development and in the adult. Studies of mice...

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Source

Identifiers

PMID: 23140631
DOI: 10.1016/B978-0-12-394592-1.00007-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Dishevelled: in vivo roles of a multifunctional gene family during development.PMID 23140631Read ↗

Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development.Semantic proximity Read ↗

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Requirement for Dlgh-1 in planar cell polarity and skeletogenesis during vertebrate development.Semantic proximity Read ↗

Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure.Semantic proximity Read ↗

Genetic analysis of disheveled 2 and disheveled 3 in human neural tube defects.Semantic proximity Read ↗

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Loss of Dact1 Disrupts Planar Cell Polarity Signaling by Altering Dishevelled Activity and Leads to Posterior Malformation in MiceSemantic proximity Read ↗

The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome.Semantic proximity Read ↗

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