Requirement of dendritic cells and B cells in the clonal deletion of Mls-reactive T cells in the thymus.

doi:10.1084/jem.173.3.539

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Article

Requirement of dendritic cells and B cells in the clonal deletion of Mls-reactive T cells in the thymus.

The Journal of experimental medicine - 1 Mar 1991

Mazda O, Watanabe Y, Gyotoku J, Katsura Y

Abstract excerpt

The present study was performed to identify cells responsible for the elimination of T cells reactive with minor lymphocyte-stimulating (Mls) antigens during T cell development. Experiments were carried out in a fetal thymus organ culture (FTOC) system. To examine the tolerance-inducing activity,...

Topics

Animals
Antigens, Surface
B-Lymphocytes
Cell Adhesion
Dendritic Cells
Fetus
Immune Tolerance
Lymphocyte Activation
Lymphocyte Depletion
Mice
Mice, Inbred C3H
Mice, Inbred CBA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Minor Lymphocyte Stimulatory Antigens

Organ Culture Techniques

Phenotype

Receptors, Antigen, T-Cell

T-Lymphocytes

Thymus Gland

Source

Open in PubMed Open full text

Identifiers

PMID: 1900074
DOI: 10.1084/jem.173.3.539
PMCID: PMC2118807

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1900074-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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