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Article

The effects of in vivo cyclosporin A administration on rat thymic dendritic cells.

Clinical and experimental immunology - 1 Jun 1994

Damoiseaux J G, Beijleveld L J, van Breda Vriesman P J

Abstract excerpt

Cyclosporin A (CsA) induces a graft-versus-host-like disease (GVHD) in lethally irradiated Lewis rats reconstituted with syngeneic bone marrow. The role of the thymus in the generation of disease has been unequivocally established. It has been suggested that the CsA-induced disappearance of thymic dendritic cells (DC) is responsible for the generation of the autoaggressive cells. In this study we quantify the...

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Source

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Identifiers

PMID: 8004822
DOI: 10.1111/j.1365-2249.1994.tb06059.x
PMCID: PMC1534557

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Source receipt: pubmed, retrieved 7 Sept 2026.

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