Article
Expression of Mls determinants in mice exhibiting the severe combined immunodeficiency (scid) mutation or X-linked immunodeficiency (xid) defect.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 1992
Roberts J L, Abe R, Shores E W, Singer A
Abstract excerpt
While Ig+ B cells appear to be the principal cell type expressing immunogenic minor lymphocyte stimulatory (Mls) determinants, both T cells and B cells are capable of mediating deletion of developing Mls-reactive thymocytes. In addition, levels of mouse mammary tumor proviral transcripts are incr...
Topics
- Animals
- Genetic Linkage
- Immunologic Deficiency Syndromes
- Lymphocyte Activation
- Male
- Mice
- Mice, Inbred Strains
- Mice, SCID
- Minor Lymphocyte Stimulatory Antigens
- Mutation
- Receptors, Antigen, T-Cell
- T-Lymphocytes
- X Chromosome