Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association of interferon-alpha subtypes 1, 2 and 5 in systemic lupus erythematosus.

Tissue antigens - 1 Dec 2008

Hirankarn N, Tangwattanachuleeporn M, Wongpiyabovorn J, Wongchinsri J, Avihingsanon Y

Abstract excerpt

In this study, the association between the systemic lupus erythematosus (SLE) susceptibility and the new candidate genes, IFNA1, IFNA2 and IFNA5 genes, major interferon-alpha subtypes, in responses to viral infection was investigated. Allele and genotype frequencies of each marker were compared between 150 SLE patients and 150 healthy control subjects. This study indicated that the A/A genotype of IFNA5 (-2529)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Frequency
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-alpha

Share to Linkage Disequilibrium

Share to Lupus Erythematosus, Systemic

Share to Polymorphism, Genetic

Share to Thailand

Source

Identifiers

PMID: 19000144
DOI: 10.1111/j.1399-0039.2008.01146.x

Genes

IFNA1
IFNA5
IFNA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association of interferon-alpha subtypes 1, 2 and 5 in systemic lupus erythematosus.PMID 19000144Read ↗

Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with Asian SLE patients.Semantic proximity Read ↗

A compass that points to lupus: genetic studies on type I interferon pathway.Semantic proximity Read ↗

Variations in the interferon and TLR3 genes may be associated with susceptibility to systemic lupus erythematosus and its clinical presentation.Semantic proximity Read ↗

Gene-gene interactions of IRF5, STAT4, IKZF1 and ETS1 in systemic lupus erythematosus.Semantic proximity Read ↗

Interferon Regulatory Factor 5 in the Pathogenesis of Systemic Lupus ErythematosusSemantic proximity Read ↗

The genetics and biology of Irf5-mediated signaling in lupusSemantic proximity Read ↗

Association of the IRF5 rs2070197 polymorphism with systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

Optimal Selection of IFN-α-Inducible Genes to Determine Type I Interferon Signature Improves the Diagnosis of Systemic Lupus ErythematosusSemantic proximity Read ↗

Genetic associations in type I interferon related pathways with autoimmunity.Semantic proximity Read ↗

Association of IRF5 polymorphisms with activation of the interferon alpha pathway.Semantic proximity Read ↗

Single-cell RNA-seq reveals a persistent interferon signature in immune cells from Systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatmentSemantic proximity Read ↗

Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.