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Article

Genetic associations in type I interferon related pathways with autoimmunity.

Arthritis research & therapy - 1 Jan 2010

Delgado-Vega Angélica M, Alarcón-Riquelme Marta E, Kozyrev Sergey V

Abstract excerpt

Type I interferons play an outstanding role in innate and adaptive immunity by enhancing functions of dendritic cells, inducing differentiation of monocytes, promoting immunoglobulin class switching in B cells and stimulating effector functions of T cells. The increased production of IFNα/β by plasmacytoid dendritic cells could be responsible for not only efficient antiviral defence, but it also may be a...

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Identifiers

PMID: 20392289
DOI: 10.1186/ar2883
PMCID: PMC2991775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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