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Article

Association of IRF5 polymorphisms with activation of the interferon alpha pathway.

Annals of the rheumatic diseases - 1 Mar 2010

Rullo Ornella J, Woo Jennifer M P, Wu Hui, Hoftman Alice D C, Maranian Paul, Brahn Brittany A, McCurdy Deborah, Cantor Rita M, Tsao Betty P

Abstract excerpt

OBJECTIVE: The genetic association of interferon regulatory factor 5 (IRF5) with systemic lupus erythematosus (SLE) susceptibility has been convincingly established. To gain understanding of the effect of IRF5 variation in individuals without SLE, a study was undertaken to examine whether such genetic variation predisposes to activation of the interferon alpha (IFNalpha) pathway. METHODS: Using a computer...

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Identifiers

PMID: 19854706
DOI: 10.1136/ard.2009.118315
PMCID: PMC3135414

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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