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Article

Variations in the interferon and TLR3 genes may be associated with susceptibility to systemic lupus erythematosus and its clinical presentation.

Immunobiology - 1 Jul 2024

Modzelewska E, Wajda A, Lutkowska A, Felis-Giemza A, Stypińska B, Matusiewicz A, Puszczewicz M, Majewski D, Jagodziński P P, Haładyj E, Paradowska-Gorycka A

Abstract excerpt

The study aimed to explore the pontential impact of 10 polymorphisms within IFN-α, IFN-β1, IFN-γ and TLR3 genes on SLE phenotype and susceptibility and to study the relationship between specific genotypes and clinics. Whole blood samples from SLE patients and healthy controls was obtained. DNA was extracted from the peripheral blood by the QIAamp DNA Blood Mini Kit (Qiagen). The quality and quantity of isolated...

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Identifiers

PMID: 38821752
DOI: 10.1016/j.imbio.2024.152807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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