Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.

doi:10.1002/art.30356

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Article

Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.

Arthritis and rheumatism - 1 Jul 2011

Ramos Paula S, Williams Adrienne H, Ziegler Julie T, Comeau Mary E, Guy Richard T, Lessard Christopher J, Li He, Edberg Jeffrey C, Zidovetzki Raphael, Criswell Lindsey A, Gaffney Patrick M, Graham Deborah Cunninghame, Graham Robert R, Kelly Jennifer A, Kaufman Kenneth M, Brown Elizabeth E, Alarcón Graciela S, Petri Michelle A, Reveille John D, McGwin Gerald, Vilá Luis M, Ramsey-Goldman Rosalind, Jacob Chaim O, Vyse Timothy J, Tsao Betty P, Harley John B, Kimberly Robert P, Alarcón-Riquelme Marta E, Langefeld Carl D, Moser Kathy L

Abstract excerpt

OBJECTIVE: The overexpression of interferon (IFN)-inducible genes is a prominent feature of systemic lupus erythematosus (SLE); it serves as a marker for active and more severe disease, and is also observed in other autoimmune and inflammatory conditions. This study was undertaken to investigate...

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PMID: 21437871
DOI: 10.1002/art.30356
PMCID: PMC3128183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21437871-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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